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Neem

Indian subcontinent; Azadirachta indica, now grown across tropical Asia, Africa and the Middle East.

Blood SugarImmunitySkin

Names in Different Languages

EnglishNeem
Urduنیم
Hindiनीम
Farsiنیم
UnaniNeem
FrenchMargousier
GermanNeem

Traditional Uses

In Ayurveda and Unani medicine, neem leaf, bark and oil have long been used for skin conditions, dental care (neem twigs), blood purification in traditional terms, and as an insect repellent.

Modern Research

Neem leaf compounds show antibacterial, antifungal and anti-inflammatory activity in laboratory studies, and some small trials support dental and skin uses. Human clinical evidence is limited, and neem seed oil is toxic if swallowed, especially for children.

Uses

  • Skin care (leaf paste, oil for external use)
  • Dental care (traditional twig brushing)
  • Blood-sugar support (traditional)
  • Insect repellent (oil, external)

Benefits of Use

  • Skin support: antibacterial and antifungal activity may help minor skin irritation and acne-prone skin
  • Dental support: traditional use for gum health, with some small-study support
  • Immune support: traditional tonic use, with laboratory evidence of immune-modulating compounds
  • Blood-sugar support: traditional use, with limited human trial evidence

Safe Dose & Overdose (mg/g)

Raw Herb Form

Safe: 1,000-3,000 mg/day dried leaf powder for general use (Ayurvedic sources commonly use 1,000-3,000 mg twice daily, i.e. up to 6,000 mg/day).

Overdose: Above 6,000 mg/day: gastric discomfort and diarrhoea; 10,000 mg/day linked to nausea and liver enzyme elevation; neem seed oil ingestion is toxic, especially in children.

Extract Form

Safe: 250-1,000 mg/day standardized neem leaf extract short-term (tablets commonly 250-500 mg twice daily).

Overdose: Not established

Side Effects

  • Gastric discomfort and diarrhoea at high doses
  • Nausea and liver enzyme elevation at very high doses
  • Neem seed oil swallowed is toxic, especially in children, and can cause vomiting, drowsiness and seizures
  • Skin irritation from undiluted oil in sensitive users

Interactions

  • Blood thinners: may increase bleeding risk
  • Diabetes medicines: may add to blood-sugar-lowering effects
  • Immunosuppressant drugs: neem may stimulate immune activity and reduce their effect
  • Lithium: neem may alter lithium levels

Sources

Disclaimer

General information only — not medical advice. Consult a qualified healthcare professional before use.

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